Drosophila Neural Stem Cells in Brain Development and Tumor Formation

Jiang, Yanrui and Reichert, Heinrich. (2014) Drosophila Neural Stem Cells in Brain Development and Tumor Formation. Journal of neurogenetics, Vol. 12. pp. 181-189.

PDF - Accepted Version

Official URL: http://edoc.unibas.ch/dok/A6271908

Downloads: Statistics Overview


Neuroblasts, the neural stem cells in Drosophila, generate the complex neural structure of the central nervous system. Significant progress has been made in understanding the mechanisms regulating the self-renewal, proliferation, and differentiation in Drosophila neuroblast lineages. Deregulation of these mechanisms can lead to severe developmental defects and the formation of malignant brain tumors. Here, the authors review the molecular genetics of Drosophila neuroblasts and discuss some recent advances in stem cell and cancer biology using this model system.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Former Organization Units Biozentrum > Molecular Zoology (Reichert)
UniBasel Contributors:Reichert, Heinrich
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Informa Healthcare
Note:Publication type according to Uni Basel Research Database: Journal article
Related URLs:
Identification Number:
edoc DOI:
Last Modified:31 Dec 2015 10:56
Deposited On:05 Dec 2014 09:45

Repository Staff Only: item control page