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The preeclampsia biomarkers soluble fms-like tyrosine kinase-1 and placental growth factor : current knowledge, clinical implications and future application

Lapaire, Olav and Shennan, Andrew and Stepan, Holger. (2010) The preeclampsia biomarkers soluble fms-like tyrosine kinase-1 and placental growth factor : current knowledge, clinical implications and future application. European journal of obstetrics, gynecology, and reproductive biology, Vol. 151, H. 2. pp. 122-129.

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Official URL: http://edoc.unibas.ch/dok/A6007490

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Abstract

Preeclampsia is a leading cause of maternal and fetal/neonatal morbidity and mortality worldwide. Currently there is no single reliable parameter for the diagnosis of preeclampsia and attention has turned towards identifying non-invasive testing methods, including Doppler sonography and blood-borne or urinary biomarkers in women who go on to develop preeclampsia. Biomarkers of angiogenesis are currently at the most advanced state of development for the diagnosis of preeclampsia. In this article we will highlight the diagnostic potential of the novel biomarkers soluble fms-like tyrosine kinase-1 and placental growth factor and discuss the opportunities and challenges involved in bringing these preeclampsia biomarkers from bench to bedside.
Faculties and Departments:03 Faculty of Medicine > Bereich Spezialfächer (Klinik) > Gynäkologie und Geburtshilfe > Gynäkologie (Heinzelmann)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Spezialfächer (Klinik) > Gynäkologie und Geburtshilfe > Gynäkologie (Heinzelmann)
UniBasel Contributors:Lapaire-Mayer, Olav Carl
Item Type:Article, refereed
Article Subtype:Further Journal Contribution
Bibsysno:Link to catalogue
Publisher:Elsevier
ISSN:0301-2115
Note:Publication type according to Uni Basel Research Database: Journal item
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Last Modified:20 Jun 2014 07:55
Deposited On:20 Jun 2014 07:55

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