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Osmotic nephrosis : acute kidney injury with accumulation of proximal tubular lysosomes due to administration of exogenous solutes

Dickenmann, M. and Oettl, T. and Mihatsch, M. J.. (2008) Osmotic nephrosis : acute kidney injury with accumulation of proximal tubular lysosomes due to administration of exogenous solutes. American journal of kidney diseases, Vol. 51, H. 3. pp. 491-503.

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Official URL: http://edoc.unibas.ch/dok/A6007537

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Abstract

Osmotic nephrosis describes a morphological pattern with vacuolization and swelling of the renal proximal tubular cells. The term refers to a nonspecific histopathologic finding rather than defining a specific entity. Osmotic nephrosis can be induced by many different compounds, such as sucrose, hydroxyethyl starch, dextrans, and contrast media. It has a broad clinical spectrum that includes acute kidney injury and chronic kidney failure in rare cases. This article discusses the pathological characteristics, pathogenesis, and various clinical entities of osmotic nephrosis.
Faculties and Departments:03 Faculty of Medicine > Bereich Querschnittsfächer (Klinik) > Pathologie USB
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Querschnittsfächer (Klinik) > Pathologie USB
03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Nephrologie > Transplantationsimmunologie und Nephrologie (Steiger)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Nephrologie > Transplantationsimmunologie und Nephrologie (Steiger)
UniBasel Contributors:Mihatsch, Michael J. and Dickenmann, Michael Jan
Item Type:Article, refereed
Article Subtype:Further Journal Contribution
Bibsysno:Link to catalogue
Publisher:Saunders
ISSN:0272-6386
Note:Publication type according to Uni Basel Research Database: Journal item
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Last Modified:20 Jun 2014 07:55
Deposited On:20 Jun 2014 07:55

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