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LcrG is required for efficient translocation of Yersinia Yop effector proteins into eukaryotic cells

Sarker, M. R. and Sory, M. P. and Boyd, A. P. and Iriarte, M. and Cornelis, G. R.. (1998) LcrG is required for efficient translocation of Yersinia Yop effector proteins into eukaryotic cells. Infection and immunity, Vol. 66, H. 6. pp. 2976-2979.

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Official URL: http://edoc.unibas.ch/dok/A5259199

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Abstract

Extracellular Yersinia disables the immune system of its host by injecting effector Yop proteins into host cells. We show that a Yersinia enterocolitica nonpolar lcrG mutant is severely impaired in the translocation of YopE, YopH, YopM, YpkA/YopO, and YopP into eukaryotic cells. LcrG is thus required for efficient internalization of all the known Yop effectors.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Former Organization Units Biozentrum > Molecular Microbiology (Cornelis)
UniBasel Contributors:Cornelis, Guy R.
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:American Society for Microbiology
ISSN:1098-5522
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:22 Mar 2012 14:20
Deposited On:22 Mar 2012 13:22

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