Protracted disseminated skeletal metastases from angiosarcoma of the spleen

Jobke, B. and Werner, M. and Jundt, G. and Ostertag, H. and Freyschmidt, J.. (2010) Protracted disseminated skeletal metastases from angiosarcoma of the spleen. Clinical & experimental metastasis, Vol. 27, no. 2. pp. 117-122.

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Official URL: http://edoc.unibas.ch/dok/A6007233

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Angiosarcomas are high-grade vascular tumors associated with poor prognosis due to their aggressive nature. Occasional skeletal manifestations present commonly as osteolytic destruction. The 55-years-old patient presented in this case report had a disease-free 4 years interval between splenectomy after primary angiosarcoma of the spleen and an unusual skeletal metastatic pattern mimicking benign angiomatosis. Despite lacking radiographic evidence for a highly aggressive osseous process, the histopathological resemblance of the bone biopsy with the primary tumor manifestation and the fulminant course of disease after onset of disseminated osseous spread confirmed the malignant character of the vascular tumor. The case demonstrates the highly variable radiographic pattern and particular pathobiological behavior of vascular malignancies.
Faculties and Departments:03 Faculty of Medicine > Bereich Querschnittsfächer (Klinik) > Pathologie USB
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Querschnittsfächer (Klinik) > Pathologie USB
UniBasel Contributors:Jundt, Gernot
Item Type:Article, refereed
Article Subtype:Further Journal Contribution
Note:Publication type according to Uni Basel Research Database: Journal item
Last Modified:23 May 2014 08:34
Deposited On:23 May 2014 08:34

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