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[Successful treatment of thrombotic thrombocytopenic purpura (TTP) with Rituximab.]

Arici, B. and Trendelenburg, M.. (2008) [Successful treatment of thrombotic thrombocytopenic purpura (TTP) with Rituximab.]. Therapeutische Umschau, Vol. 65. pp. 710-712.

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Official URL: http://edoc.unibas.ch/dok/A6003519

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Abstract

A 15-year-old female patient with TTP was admitted to our hospital for further evaluation after the initial treatment with IVIG and prednisone failed. With the detection of anti-ADAMTS13 antibodies the acquired form of TTP could be diagnosed. Despite of therapeutic plasma exchange and high dose steroids no sustained remission could be achieved. However, application of rituximab led to a normalisation of platelet counts within one week allowing the termination of plasma exchanges and reduction of oral steroids. No side effects of rituximab were observed and the patient remained in clinical remission during the following months.
Faculties and Departments:03 Faculty of Medicine > Departement Biomedizin > Department of Biomedicine, University Hospital Basel > Clinical Immunology (Trendelenburg)
UniBasel Contributors:Trendelenburg, Marten
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Hans Huber
ISSN:0040-5930
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:23 May 2014 08:34
Deposited On:23 May 2014 08:34

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