edoc

Evidence and interdisciplinary consensus-based German guidelines : surgical treatment and radiotherapy of melanoma

Garbe, C. and Hauschild, A. and Volkenandt, M. and Schadendorf, D. and Stolz, W. and Reinhold, U. and Kortmann, R. D. and Kettelhack, C. and Frerich, B. and Keilholz, U. and Dummer, R. and Sebastian, G. and Tilgen, W. and Schuler, G. and Mackensen, A. and Kaufmann, R.. (2008) Evidence and interdisciplinary consensus-based German guidelines : surgical treatment and radiotherapy of melanoma. Melanoma research, Vol. 18, H. 1. pp. 61-67.

Full text not available from this repository.

Official URL: http://edoc.unibas.ch/dok/A6003508

Downloads: Statistics Overview

Abstract

The primary treatment of a melanoma is surgical excision. An excisional biopsy is preferred, and safety margins of 1 cm for tumor thickness up to 2 mm and 2 cm for higher tumor thickness should be applied either at primary excision or in a two-step procedure. When dealing with facial, acral or anogenital melanomas, micrographic control of the surgical margins may be preferable to allow reduced safety margins and conservation of tissue. The sentinel lymph node biopsy should be performed in patients whose primary melanoma is thicker than 1.0 mm and this operation should be performed in centers where both the operative and nuclear medicine teams are experienced. In clinically identified lymph node metastases, radical lymph node dissection is considered standard therapy. If distant metastases involve just one internal organ and operative removal is feasible, then surgery should be seen as therapy of choice. Radiation therapy for the primary treatment of melanoma is indicated only in those cases in which surgery is impossible or not reasonable. In regional lymph nodes, radiation therapy is usually recommended when excision is not complete (R1 resection) or if the nodes are inoperable. In distant metastases, radiation therapy is particularly indicated in bone metastases, brain metastases and soft tissue metastases.
Faculties and Departments:03 Faculty of Medicine > Bereich Operative Fächer (Klinik) > Innere Organe > Allgemein- und Viszeralchirurgie (Oertli)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Operative Fächer (Klinik) > Innere Organe > Allgemein- und Viszeralchirurgie (Oertli)
UniBasel Contributors:Kettelhack, Christoph
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Rapid Communications
ISSN:0960-8931
Note:Publication type according to Uni Basel Research Database: Journal article
Related URLs:
Identification Number:
Last Modified:25 Apr 2014 08:01
Deposited On:25 Apr 2014 08:01

Repository Staff Only: item control page