"Apical ballooning" - what is the cause?

Wani, Sunil and Glatz, Kathrin and Suter, Yves and Jamshidi, Peiman and Erne, Paul. (2008) "Apical ballooning" - what is the cause? The journal of invasive cardiology, Vol. 20. pp. 599-602.

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Official URL: http://edoc.unibas.ch/dok/A6006702

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The pathophysiology of takotsubo cardiomyopathy remains enigmatic. Here we attempted to define the link between the coronary arteries and the histopathological involvement of the left ventricle. We observed similarities and discrepancies between patients. All patients experienced stress prior to the event. We found a reduced coronary flow reserve in all patients and signs of hibernating myocardium on biopsy specimen. This raises a strong suspicion of stress-induced endothelial dysfunction with hibernating myocardium in the pathogenesis of this cardiomyopathy.
Faculties and Departments:03 Faculty of Medicine > Departement Biomedizin > Further Research Groups at DBM > Signal Transduction (Resink/Erne)
03 Faculty of Medicine > Bereich Querschnittsfächer (Klinik) > Pathologie USB
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Querschnittsfächer (Klinik) > Pathologie USB
UniBasel Contributors:Erne, Paul and Glatz-Krieger, Katharina
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:HMP Communications
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:04 Sep 2015 14:31
Deposited On:25 Apr 2014 08:00

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