Patterning of skeletal muscle

Arber, S. and Burden, S. J. and Harris, A. J.. (2002) Patterning of skeletal muscle. Current opinion in neurobiology, Vol. 12, H. 1. pp. 100-103.

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Official URL: http://edoc.unibas.ch/dok/A5259092

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Recent studies challenge the view that signals provided by motor neurons are required to activate subsynaptic nuclei and induce postsynaptic specializations in developing skeletal muscle. New findings show that acetylcholine receptor genes are expressed and that acetylcholine receptor clusters form preferentially in the prospective synaptic region of muscle independently of motor innervation. These results indicate that developing myotubes are patterned by mechanisms intrinsic to developing muscles and raise the possibility that patterning of muscles may influence the growth pattern of motor axons and the sites where synapses form.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Neurobiology > Cell Biology (Arber)
UniBasel Contributors:Arber, Silvia
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Current Biology
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:22 Mar 2012 14:20
Deposited On:22 Mar 2012 13:21

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