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Mould and dampness in dwelling places, and onset of asthma : the population-based cohort ECRHS

Norbäck, Dan and Zock, Jan-Paul and Plana, Estel and Heinrich, Joachim and Svanes, Cecilie and Sunyer, Jordi and Künzli, Nino and Villani, Simona and Olivieri, Mario and Soon, Argo and Jarvis, Deborah. (2013) Mould and dampness in dwelling places, and onset of asthma : the population-based cohort ECRHS. Occupational and environmental medicine, Vol. 70, H. 5. pp. 325-331.

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Official URL: http://edoc.unibas.ch/dok/A6165038

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Abstract

To study new onset of adult asthma in relation to dampness and moulds in dwelling places.; Totally, 7104 young adults from 13 countries who participated in the European Community Respiratory Health Survey (ECRHS I and II) who did not report respiratory symptoms or asthma at baseline were followed prospectively for 9 years. Asthma was assessed by questionnaire data on asthmatic symptoms and a positive metacholine challenge test at follow-up. Data on the current dwelling was collected at the beginning and at the end of the follow-up period by means of an interviewer-led questionnaire, and by inspection. Relative risks (RR) for new onset asthma were calculated with log-binomial models adjusted for age, sex, smoking and study centre.; There was an excess of new asthma in subjects in homes with reports on water damage (RR 1.46; 95% CI 1.09 to 1.94) and indoor moulds (RR=1.30; 95% CI 1.00 to 1.68) at baseline. A dose-response effect was observed. The effect was stronger in those with multisensitisation and in those sensitised to moulds. Observed damp spots were related to new asthma (RR=1.49; 95% CI 1.00 to 2.22). The population-attributable risk was 3-10% for reported, and 3-14% for observed dampness/moulds.; Dampness and mould are common in dwellings, and contribute to asthma incidence in adults.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Chronic Disease Epidemiology > Air Pollution and Health (Künzli)
03 Faculty of Medicine > Departement Public Health > Sozial- und Präventivmedizin > Air Pollution and Health (Künzli)
UniBasel Contributors:Künzli, Nino
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:BMJ Publ. Group
ISSN:1351-0711
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:27 Mar 2014 13:13
Deposited On:27 Mar 2014 13:13

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