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Assembly of motor circuits in the spinal cord : driven to function by genetic and experience-dependent mechanisms

Ladle, D. R. and Pecho-Vrieseling, E. and Arber, S.. (2007) Assembly of motor circuits in the spinal cord : driven to function by genetic and experience-dependent mechanisms. Neuron, Vol. 56, H. 2. pp. 270-283.

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Official URL: http://edoc.unibas.ch/dok/A5259069

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Abstract

Motor circuits in the spinal cord integrate information from various sensory and descending pathways to control appropriate motor behavior. Recent work has revealed that target-derived retrograde signaling mechanisms act to influence sequential assembly of motor circuits through combinatorial action of genetic and experience-driven programs. These parallel activities imprint somatotopic information at the level of the spinal cord in precisely interconnected circuits and equip animals with motor circuits capable of reacting to changing demands throughout life.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Neurobiology > Cell Biology (Arber)
UniBasel Contributors:Arber, Silvia
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Cell Press
ISSN:0896-6273
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:22 Mar 2012 14:20
Deposited On:22 Mar 2012 13:21

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