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Enhanced uridine bioavailability following administration of a triacetyluridine-rich nutritional supplement

Weinberg, Melissa E. and Roman, Mark C. and Jacob, Peyton and Wen, Michael and Cheung, Polly and Walker, Ulrich A. and Mulligan, Kathleen and Schambelan, Morris. (2011) Enhanced uridine bioavailability following administration of a triacetyluridine-rich nutritional supplement. PLoS ONE, Vol. 6, H. 2 , e14709.

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Official URL: http://edoc.unibas.ch/dok/A6007069

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Abstract

Uridine is a therapy for hereditary orotic aciduria and is being investigated in other disorders caused by mitochondrial dysfunction, including toxicities resulting from treatment with nucleoside reverse transcriptase inhibitors in HIV. Historically, the use of uridine as a therapeutic agent has been limited by poor bioavailability. A food supplement containing nucleosides, NucleomaxX®, has been reported to raise plasma uridine to supraphysiologic levels.
Faculties and Departments:03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Rheumatologie
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Rheumatologie
UniBasel Contributors:Walker, Ulrich A.
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Public Library of Science
e-ISSN:1932-6203
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:31 Aug 2018 06:40
Deposited On:27 Mar 2014 13:13

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