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Treatment of mucosal leishmaniasis (L. infantum) with miltefosine in a patient with Good syndrome

Stoeckle, Marcel and Holbro, Andreas and Arnold, Andreas and Neumayr, Andreas and Weisser, Maya and Blum, Johannes. (2013) Treatment of mucosal leishmaniasis (L. infantum) with miltefosine in a patient with Good syndrome. Acta tropica : Zeitschrift für Tropenwissenschaften und Tropenmedizin, 128 (1). pp. 168-170.

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Official URL: http://edoc.unibas.ch/dok/A6194646

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Abstract

We report on a 76-year old patient with recurrent mucosal leishmaniasis. Multiple treatment regimens were administered. After the second relapse, immunologic workup and review of the patient's history revealed the presence of Good syndrome, characterized by immunodeficiency in patients with thymoma. The third relapse was treated with oral miltefosine with complete resolution of the lesions. Miltefosine is an option for treating Old World leishmaniasis (Leishmania infantum) and immunodeficiency should be considered in patients with recurrent leishmaniasis.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Former Units within Swiss TPH > Medical Practice Föhre (Blum)
UniBasel Contributors:Blum, Johannes A. and Neumayr, Andreas
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Elsevier Science Publ.
ISSN:0001-706X
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:05 Sep 2018 10:01
Deposited On:27 Feb 2014 15:46

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