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[Testosterone and bone: indications and limitations]

Stoll, Delphine and Puder, Jardena J. and Lamy, Olivier. (2011) [Testosterone and bone: indications and limitations]. Revue médicale suisse, Vol. 7, no. 299. pp. 1311-1315.

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Official URL: http://edoc.unibas.ch/dok/A6004665

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Abstract

Osteoporosis incidence increases exponentially with age in men and hypogonadism represents a risk factor. Sex steroids levels are correlated to bone mineral density and to fracture prevalence. Most studies demonstrate an improvement in bone mineral density in men with hypogonadism as a result of testosterone therapy. Nevertheless there are no data evaluating the effect of testosterone therapy on fractures in men. Approximately 20% of men older than 60 have a total testosterone level lower than the lower limit of the reference range but there is no true consensus on the definition of hypogonadism in older men. In older men we recommend to treat only if total morning testosterone levels are > 8 nmol/l or even > 6,9 nmol/l on several occasions in the absence of any reversible illness and if there is no contraindication for treatment.
Faculties and Departments:03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Endokrinologie / Diabetologie
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Endokrinologie / Diabetologie
UniBasel Contributors:Puder, Jardena
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Médecine & hygiène
ISSN:1660-9379
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:27 Feb 2014 15:45
Deposited On:27 Feb 2014 15:45

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