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Increased 90-day mortality in patients with acute heart failure with elevated copeptin : secondary results from the Biomarkers in Acute Heart Failure (BACH) study

Maisel, Alan and Xue, Yang and Shah, Kevin and Mueller, Christian and Nowak, Richard and Peacock, W. Frank and Ponikowski, Piotr and Mockel, Martin and Hogan, Christopher and Wu, Alan H. B. and Richards, Mark and Clopton, Paul and Filippatos, Gerasimos S. and Di Somma, Salvatore and Anand, Inder S. and Ng, Leong and Daniels, Lori B. and Neath, Sean-Xavier and Christenson, Robert and Potocki, Mihael and McCord, James and Terracciano, Garret and Kremastinos, Dimitrios and Hartmann, Oliver and von Haehling, Stephan and Bergmann, Andreas and Morgenthaler, Nils G. and Anker, Stefan D.. (2011) Increased 90-day mortality in patients with acute heart failure with elevated copeptin : secondary results from the Biomarkers in Acute Heart Failure (BACH) study. Circulation. Heart failure, Vol. 4, H. 5. pp. 613-620.

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Official URL: http://edoc.unibas.ch/dok/A6006474

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Abstract

In patients with heart failure (HF), increased arginine vasopressin concentrations are associated with more severe disease, making arginine vasopressin an attractive target for therapy. However, AVP is difficult to measure due to its in vitro instability and rapid clearance. Copeptin, the C-terminal segment of preprovasopressin, is a stable and reliable surrogate biomarker for serum arginine vasopressin concentrations.
Faculties and Departments:03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Kardiologie > Klinische Outcomeforschung Kardiologie (Müller)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Kardiologie > Klinische Outcomeforschung Kardiologie (Müller)
UniBasel Contributors:Müller, Christian
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Lippincott
ISSN:1941-3297
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:27 Feb 2014 15:45
Deposited On:27 Feb 2014 15:45

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