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Clinical EEG in cognitively impaired patients with Parkinson's Disease

Schlede, Nina and Zimmermann, Ronan and Ehrensperger, Michael M. and Gschwandtner, Ute and Hardmeier, Martin and Hatz, Florian and Monsch, Andreas U. and Naegelin, Yvonne and Fuhr, Peter. (2011) Clinical EEG in cognitively impaired patients with Parkinson's Disease. Journal of the neurological sciences, Vol. 310, No. 1-2. pp. 75-78.

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Official URL: http://edoc.unibas.ch/dok/A6007066

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Abstract

Parkinson's Disease Dementia (PD-D) is one of the most important non-motor signs in advanced PD and is the most influencing factor predicting nursing home placement. PD-related Mild Cognitive Impairment (PD-MCI) is a potential prodromal stage of PD-D. The Grand Total EEG (GTE) score is a rating scale for clinical EEG (Electroencephalography) analyses which is useful in the evaluation of different types of dementia. The purpose of the present study was to investigate the relationship between a short version of the GTE score and severity of cognitive deficits in PD. Nineteen patients with PD underwent neuropsychological testing and resting state EEG. Significant correlations with deteriorating cognition (combined Mini Mental Status Examination/Clock Drawing Test) were found for the overall short GTE score (Spearman Rank correlation, ?=-.6; p>.05) and for the subscore "Frequency of Rhythmic Background Activity" (?=-.6; p>.05), indicating that these EEG measures increase with deteriorating cognition.
Faculties and Departments:03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Neurologie
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Neurologie
03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Neurologie > Neuroimmunologie (Kappos)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Neurologie > Neuroimmunologie (Kappos)
03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Geriatrie
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Geriatrie
07 Faculty of Psychology > Departement Psychologie
UniBasel Contributors:Monsch, Andreas U and Fuhr, Peter and Gschwandtner, Ute
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Elsevier
ISSN:0022-510X
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:27 Feb 2014 15:45
Deposited On:27 Feb 2014 15:45

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