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Anti-C1q autoantibodies do not correlate with the occurrence or severity of experimental lupus nephritis

Bigler, C. and Hopfer, H. and Danner, D. and Schaller, M. and Mihatsch, M. J. and Trendelenburg, M.. (2011) Anti-C1q autoantibodies do not correlate with the occurrence or severity of experimental lupus nephritis. Nephrology, dialysis, transplantation, Vol. 26, H. 4. pp. 1220-1228.

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Official URL: http://edoc.unibas.ch/dok/A6004737

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Abstract

In systemic lupus erythematosus patients, a strong association between the occurrence of antibodies against complement C1q (anti-C1q) and lupus nephritis can be observed. However, the predictive value of anti-C1q titres for a renal flare remains to be determined. Increasing titres of anti-C1q before the occurrence of clinical apparent nephritis might not only serve as a clinical parameter but also indicate a direct pathogenic mechanism of anti-C1q.
Faculties and Departments:03 Faculty of Medicine > Departement Biomedizin > Department of Biomedicine, University Hospital Basel > Clinical Immunology (Trendelenburg)
03 Faculty of Medicine > Bereich Querschnittsfächer (Klinik) > Pathologie USB
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Querschnittsfächer (Klinik) > Pathologie USB
UniBasel Contributors:Mihatsch, Michael J. and Trendelenburg, Marten
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Oxford University Press
ISSN:0931-0509
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:08 May 2015 08:45
Deposited On:27 Feb 2014 15:45

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