edoc

Metastatic colon cancer cells negotiate the intravasation notch

Christofori, Gerhard. (2011) Metastatic colon cancer cells negotiate the intravasation notch. Cancer cell, Vol. 19, H. 1. pp. 6-8.

Full text not available from this repository.

Official URL: http://edoc.unibas.ch/dok/A6006418

Downloads: Statistics Overview

Abstract

In this issue of Cancer Cell, Sonoshita et al. report that Aes/Grg5 prevents metastasis of colorectal cancer cells by sequestering and inactivating Notch transcriptional effectors in distinct nuclear foci. Loss of Aes/Grg5 in invasive cancer cells where Notch is activated by stroma-expressed ligands promotes invasion, transendothelial migration, intravasation, and metastasis.
Faculties and Departments:03 Faculty of Medicine > Departement Biomedizin > Division of Biochemistry and Genetics > Tumor Biology (Christofori)
UniBasel Contributors:Christofori, Gerhard M.
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Cell Press
ISSN:1535-6108
Note:Publication type according to Uni Basel Research Database: Journal article
Related URLs:
Identification Number:
Last Modified:10 Apr 2015 09:13
Deposited On:13 Sep 2013 07:49

Repository Staff Only: item control page