Delayed functional maturation of human neuronal progenitor cells in vitro

Lepski, G. and Maciaczyk, J. and Jannes, C. E. and Maciaczyk, D. and Bischofberger, J. and Nikkhah, G.. (2011) Delayed functional maturation of human neuronal progenitor cells in vitro. Molecular and cellular neuroscience, Vol. 47, H. 1. pp. 36-44.

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Official URL: http://edoc.unibas.ch/dok/A6005103

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Differentiation of neuronal progenitor cells (NPCs) in vitro into functional neurons is dependent on a complex cascade of molecular signaling pathways, many of which remain unknown. More specifically, in human NPCs the relationship between the expression of typical neuronal marker proteins and functional properties, such as firing action potential and synaptic transmission, is not well understood. In the present report, the immunocytochemical, morphological and electrophysiological changes that human NPCs undergo during neuronal differentiation in vitro were investigated.
Faculties and Departments:03 Faculty of Medicine > Departement Biomedizin > Division of Physiology > Cellular Neurophysiology (Bischofberger)
UniBasel Contributors:Bischofberger, Josef
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Academic Press
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:10 Apr 2015 09:13
Deposited On:16 Aug 2013 07:33

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