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Systematic review of reviews including animal studies addressing therapeutic interventions for sepsis

Lamontagne, François and Briel, Matthias and Duffett, Mark and Fox-Robichaud, Alison and Cook, Deborah J. and Guyatt, Gordon and Lesur, Olivier and Meade, Maureen O.. (2010) Systematic review of reviews including animal studies addressing therapeutic interventions for sepsis. Critical care medicine, Vol. 38, H. 12. pp. 2401-2408.

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Official URL: http://edoc.unibas.ch/dok/A6007406

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Abstract

Certain methodologic features of animal experiments such as random assignment have been found to reduce the risk of bias. Because animal research sometimes informs clinical practice, explicit acknowledgment of the risk of bias and clinical relevance cultivates realistic expectations on the part of clinicians reading preclinical studies. We assessed literature reviews of therapeutic interventions for sepsis that include animal experiments for explicit appraisals of the risk of bias and clinical relevance.
Faculties and Departments:03 Faculty of Medicine > Departement Klinische Forschung > Clinical Epidemiology and Biostatistics CEB > Klinische Epidemiologie (Bucher H)
UniBasel Contributors:Briel, Matthias
Item Type:Article, refereed
Article Subtype:Further Journal Contribution
Bibsysno:Link to catalogue
Publisher:Lippincott Williams & Wilkins
ISSN:0090-3493
Note:Publication type according to Uni Basel Research Database: Journal item
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Last Modified:19 Jul 2013 07:44
Deposited On:19 Jul 2013 07:41

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