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Cloning and sequencing of mouse skeletal muscle alpha-dystroglycan

Brancaccio, A. and Ruegg, M. A. and Engel, J.. (1995) Cloning and sequencing of mouse skeletal muscle alpha-dystroglycan. Matrix biology, Vol. 14, H. 8. pp. 681-685.

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Abstract

alpha-Dystroglycan has attracted much interest due to its important function in linking laminin in the extracellular matrix and dystrophin in the muscle. The complete sequence of mouse skeletal muscle alpha-dystroglycan was produced and cloned by applying the reverse transcriptase-polymerase chain reaction approach to the total RNA extracted from the mouse myogenic cell line C2C12. The results demonstrate the usefulness of this approach and the high degree of conservation of alpha-dystroglycan between different species, and they provide the basis for additional work with the murine species.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Neurobiology > Pharmacology/Neurobiology (Rüegg)
UniBasel Contributors:Rüegg, Markus A.
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Elsevier Science
ISSN:0945-053X
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Identification Number:
Last Modified:17 Apr 2019 11:53
Deposited On:22 Mar 2012 13:20

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