Agrin, laminin beta 2 (s-laminin) and ARIA : their role in neuromuscular development

Ruegg, M. A.. (1996) Agrin, laminin beta 2 (s-laminin) and ARIA : their role in neuromuscular development. Current Opinion in Neurobiology, Vol. 6, H. 1. pp. 97-103.

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Development of pre- and postsynaptic specializations at the vertebrate neuromuscular junction is affected by molecules concentrated in the extracellular matrix of the synaptic cleft. Agrin, laminin beta 2 and ARIA are the best characterized proteins known to be involved in particular aspects of synaptic differentiation. Recent advances in defining the domains of these molecules that are crucial for their synapse-organizing activity and their localization to synaptic basal lamina will help our understanding of the molecular mechanisms involved in synapse formation.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Neurobiology > Pharmacology/Neurobiology (Rüegg)
UniBasel Contributors:Rüegg, Markus A.
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:17 Apr 2019 11:42
Deposited On:22 Mar 2012 13:20

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