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Eosinophilic oesophagitis : latest intelligence

Schoepfer, A. M. and Simon, D. and Straumann, A.. (2011) Eosinophilic oesophagitis : latest intelligence. Clinical & experimental allergy, Vol. 41, H. 5. pp. 630-639.

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Official URL: http://edoc.unibas.ch/dok/A6007324

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Abstract

Eosinophilic oesophagitis (EoE), first described in the early 1990s, has rapidly evolved as a distinctive chronic inflammatory oesophageal disease with increasing incidence and prevalence in the westernized countries. Currently, EoE represents the main cause of dysphagia in adult patients. This disease is more prevalent in males and is frequently associated with allergies. The diagnosis is established based on the presence of oesophageal symptoms and dense eosinophilic oesophageal infiltration once other conditions leading to oesophageal eosinophilia are excluded. It is currently under discussion to what extent and by which methods allergic testing should be performed. Topical corticosteroids lead to a rapid improvement of active EoE clinically and histologically. Especially in children, elimination diets can have similar efficacy as topical corticosteroids. Oesophageal dilation of EoE-induced oesophageal strictures can also be effective in improving symptoms, but this therapy has no effect on the underlying inflammation. Neither the diagnostic nor the long-term therapeutic strategies are as yet defined.
Faculties and Departments:03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Gastroenterologie
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Gastroenterologie
UniBasel Contributors:Straumann, Alex
Item Type:Article, refereed
Article Subtype:Further Journal Contribution
Bibsysno:Link to catalogue
Publisher:Blackwell
ISSN:0954-7894
Note:Publication type according to Uni Basel Research Database: Journal item
Identification Number:
Last Modified:21 Jun 2013 12:29
Deposited On:21 Jun 2013 12:28

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