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The Role of Dystroglycan and Its Ligands in Physiology and Disease

Meier, T. and Ruegg, M. A.. (2000) The Role of Dystroglycan and Its Ligands in Physiology and Disease. News in physiological sciences, Vol. 15. pp. 255-259.

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Official URL: http://edoc.unibas.ch/dok/A5258412

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Abstract

Dystroglycan contributes to the formation of basement membrane during embryonic development and enforces cell membrane integrity by bridging cytoskeleton and components of the extracellular matrix. In several forms of muscle disease, dystroglycan is reduced in abundance. Moreover, human viral and bacterial pathogens use dystroglycan as their cellular entry point.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Neurobiology > Pharmacology/Neurobiology (Rüegg)
UniBasel Contributors:Rüegg, Markus A.
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:International Union of Physiological Sciences and the American Physiological Society
ISSN:0886-1714
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:22 Mar 2012 14:20
Deposited On:22 Mar 2012 13:20

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