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Vaskuläres Altern, Hypertonie und körperliche Aktivität = Vascular aging, arterial hypertension and physical activity

Schmidt-Trucksäss, A. and Weisser, B.. (2011) Vaskuläres Altern, Hypertonie und körperliche Aktivität = Vascular aging, arterial hypertension and physical activity. Deutsche medizinische Wochenschrift, Jg. 136, H. 46. pp. 2367-2371.

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Official URL: http://edoc.unibas.ch/dok/A6007579

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Abstract

The present review delineates the significance of intima-media-thickness, arterial stiffness and endothelial function for vascular aging. There is profound evidence for an increase in intima-media-thickness and vascular stiffness not only during healthy aging but induced also by cardiovascular risk factors. There is a central role of arterial hypertension for this progression in both structural factors. In addition, both parameters are strongly associated with cardiovascular risk. Endothelial function measured as postischemic flow-mediated vasodilatation is a functional parameter which is decreased both in healthy aging and by cardiovascular risk factors. Physical activity modifies the influence of aging and risk factors on endothelial function. A positive influence of endurance exercise on vascular stiffness and endothelial function has been demonstrated in numerous studies. In long-term studies, regular physical activity has been shown to reduce the progression of intima-media-thickness. Thus, arterial hypertension accelerates vascular aging, while physical activity has a positive influence on a variety of vascular parameters associated with vascular aging.
Faculties and Departments:03 Faculty of Medicine > Departement Sport, Bewegung und Gesundheit > Bereich Sport- und Bewegungsmedizin > Sportmedizin (Schmidt-Trucksäss)
UniBasel Contributors:Schmidt-Trucksäss, Arno
Item Type:Article, refereed
Article Subtype:Further Journal Contribution
Bibsysno:Link to catalogue
Publisher:Thieme
ISSN:0012-0472
Note:Publication type according to Uni Basel Research Database: Journal item
Identification Number:
Last Modified:21 Jun 2013 12:29
Deposited On:21 Jun 2013 12:24

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