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Molecular analysis of aquaporin genes 1 to 4 in patients with Menière's disease

Candreia, Claudia and Schmuziger, Nicolas and Gürtler, Nicolas. (2010) Molecular analysis of aquaporin genes 1 to 4 in patients with Menière's disease. Kosmos Studienbücher. pp. 787-792.

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Official URL: http://edoc.unibas.ch/dok/A6006277

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Abstract

Menière's Disease (MD) is an episodic cochleovestibular dysfunction of unknown etiology, still lacking a specific test and therapy. The proposed theories on the pathophysiology include genetic factors and factors relating to inner ear homeostasis. Various aquaporins (AQP), water channels, expressed in the inner ear and the vestibular organ, are involved in homeostasis. Mutations in AQP genes could result in disturbed inner ear homeostasis and endolymphatic hydrops, and therefore be involved in the pathogenesis of MD. Aim: To search for mutations in AQP1 to 4 in patients suffering from MD.
Faculties and Departments:03 Faculty of Medicine > Bereich Spezialfächer (Klinik) > Otorhinolaryngologie
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Spezialfächer (Klinik) > Otorhinolaryngologie
03 Faculty of Medicine > Bereich Spezialfächer (Klinik) > Ehemalige Einheiten Spezialfächer (Klinik) > Oto-Rhino-Laryngologie AG (Podvinec)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Spezialfächer (Klinik) > Ehemalige Einheiten Spezialfächer (Klinik) > Oto-Rhino-Laryngologie AG (Podvinec)
UniBasel Contributors:Schmuziger, Nicolas Michel and Gürtler, Nicolas A.L.
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Note:Also published in: Cellular physiology and biochemistry. - Basel : Karger. - Vol. 26, H. 4/5 (2010), S. 787-792 -- Publication type according to Uni Basel Research Database: Journal article
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Last Modified:24 May 2013 09:23
Deposited On:24 May 2013 09:20

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