Clinical evaluation of the adult who has eosinophilic esophagitis

Straumann, A.. (2009) Clinical evaluation of the adult who has eosinophilic esophagitis. Immunology and allergy clinics of North America, Vol. 29. pp. 11-18.

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Official URL: http://edoc.unibas.ch/dok/A6005238

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Eosinophilic esophagitis (EoE) is a rapidly increasing, chronic, T helper 2-type inflammatory disease of the esophagus characterized by esophagus related symptoms and a dense esophageal eosinophilia, both of which are refractory to proton pump inhibitors. The adult patient presents with a typical history of dysphagia for solids and has often experienced food impactions. However the general appearance shows an apparently healthy individual; the physical examination is usually unremarkable. The endoscopic findings are often subtle and misleading. The diagnosis is therefore based on the histologic finding of a dense eosinophilic infiltration of the esophageal mucosa. In adult patients, topical and systemic corticosteroids, leukotriene receptor antagonists, immunomodulators, and dilation have proven efficacy, whereas therapy with diet is still under evaluation.
Faculties and Departments:03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Gastroenterologie
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Gastroenterologie
UniBasel Contributors:Straumann, Alex
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:W. B. Saunders
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:24 May 2013 09:21
Deposited On:24 May 2013 08:58

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