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Principles and practice of thromboelastography in clinical coagulation management and transfusion practice

Bolliger, Daniel and Seeberger, Manfred D. and Tanaka, Kenichi A.. (2012) Principles and practice of thromboelastography in clinical coagulation management and transfusion practice. Transfusion medicine reviews, Vol. 26, H. 1. pp. 1-13.

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Official URL: http://edoc.unibas.ch/dok/A6004042

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Abstract

In the recent years, thromboelastography has become a popular monitoring device for hemostasis and transfusion management in major surgery, trauma, and hemophilia. Thromboelastography is performed in whole blood and assesses the viscoelastic property of clot formation under low shear condition. Thromboelastography can be performed with a variety of activator and inhibitors at different concentrations representing the most important factors for different intervals and clot formation variables reported in multiple studies and algorithms. Furthermore, fibrinogen levels and platelet counts have a major influence on thromboelastographic variables. In addition, differences in patient populations, devices, and preanalytical conditions contribute to some conflicting findings in different studies.
Faculties and Departments:03 Faculty of Medicine > Bereich Querschnittsfächer (Klinik) > Anästhesiologie
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Querschnittsfächer (Klinik) > Anästhesiologie
UniBasel Contributors:Seeberger-Stucky, Manfred
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Elsevier
ISSN:0887-7963
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:24 May 2013 09:12
Deposited On:26 Apr 2013 07:00

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