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Donor-derived aspergillosis from use of a solid organ recipient as a multiorgan donor

Mueller, N. J. and Weisser, M. and Fehr, T. and Wüthrich, R. P. and Müllhaupt, B. and Lehmann, R. and Imhof, A. and Aubert, J.-D. and Genoni, M. and Kunz, R. and Weber, M. and Steiger, J.. (2010) Donor-derived aspergillosis from use of a solid organ recipient as a multiorgan donor. Transplant infectious disease, Vol. 12, H. 1. pp. 54-59.

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Official URL: http://edoc.unibas.ch/dok/A6006396

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Abstract

The growing need for organs and the scarcity of donors has resulted in an increased use of extended criteria donors. We report a case where a recipient of a cardiac graft was used as an organ donor. Death of the recipient occurred 9 days after transplantation and was attributed to presumed cerebral hemorrhage, which post mortem was diagnosed as invasive aspergillosis of the brain. One recipient of a kidney transplant lost the graft due to infection with Aspergillus fumigatus, whereas prompt initiation of therapy successfully prevented disseminated aspergillosis in the other recipients. Despite the pressure to extend the use of organs by lowering the acceptance criteria, organs should only be accepted if the cause of death of the donors is unequivocally explained.
Faculties and Departments:03 Faculty of Medicine > Departement Klinische Forschung > Clinical Epidemiology and Biostatistics CEB > Klinische Epidemiologie (Bucher H)
03 Faculty of Medicine > Departement Biomedizin > Former Units at DBM > Transplantation Immunology and Nephrology (Palmer/Steiger)
UniBasel Contributors:Steiger, Jürg U. and Kunz, Regina
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Blackwell
ISSN:1399-3062
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:24 May 2013 09:14
Deposited On:26 Apr 2013 06:56

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