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A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis

Kappos, Ludwig and Radue, Ernst-Wilhelm and O'Connor, Paul and Polman, Chris and Hohlfeld, Reinhard and Calabresi, Peter and Selmaj, Krzysztof and Agoropoulou, Catherine and Leyk, Malgorzata and Zhang-Auberson, Lixin and Burtin, Pascale and Freedoms Study Group, . (2010) A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis. The New England journal of medicine, Vol. 362, H. 5. pp. 387-401.

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Official URL: http://edoc.unibas.ch/dok/A6006665

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Abstract

Oral fingolimod, a sphingosine-1-phosphate-receptor modulator that prevents the egress of lymphocytes from lymph nodes, significantly improved relapse rates and end points measured on magnetic resonance imaging (MRI), as compared with either placebo or intramuscular interferon beta-1a, in phase 2 and 3 studies of multiple sclerosis.
Faculties and Departments:03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Neurologie > Neuroimmunologie (Kappos)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Neurologie > Neuroimmunologie (Kappos)
UniBasel Contributors:Kappos, Ludwig
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Massachusetts Medical Society
ISSN:1533-4406
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:26 Apr 2013 07:02
Deposited On:26 Apr 2013 06:54

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