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Defective phagocytosis of apoptotic cells by macrophages in atherosclerotic lesions of ob/ob mice and reversal by a fish oil diet

Li, Suzhao and Sun, Yu and Liang, Chien-Ping and Thorp, Edward B. and Han, Seongah and Jehle, Andreas W. and Saraswathi, Viswanathan and Pridgen, Brian and Kanter, Jenny E. and Li, Rong and Welch, Carrie L. and Hasty, Alyssa H. and Bornfeldt, Karin E. and Breslow, Jan L. and Tabas, Ira and Tall, Alan R.. (2009) Defective phagocytosis of apoptotic cells by macrophages in atherosclerotic lesions of ob/ob mice and reversal by a fish oil diet. Circulation research : journal of the American Heart Association, Vol. 105. pp. 1072-1082.

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Official URL: http://edoc.unibas.ch/dok/A6004725

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Abstract

The complications of atherosclerosis are a major cause of death and disability in type 2 diabetes. Defective clearance of apoptotic cells by macrophages (efferocytosis) is thought to lead to increased necrotic core formation and inflammation in atherosclerotic lesions.
Faculties and Departments:03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Ehemalige Einheiten Medizinische Fächer (Klinik) > Allgemeine innere Medizin Bruderholz (Krapf)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Ehemalige Einheiten Medizinische Fächer (Klinik) > Allgemeine innere Medizin Bruderholz (Krapf)
UniBasel Contributors:Jehle, Andreas Werner
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Lippincott Williams & Wilkins
ISSN:0009-7330
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:01 Mar 2013 11:14
Deposited On:01 Mar 2013 11:10

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