Malachite green derivatives for two-photon RNA detection

Lux, J. and Pena, E. J. and Bolze, F. and Heinlein, M. and Nicoud, J. F.. (2012) Malachite green derivatives for two-photon RNA detection. ChemBioChem, Vol. 13, H. 8. pp. 1206-1213.

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Official URL: http://edoc.unibas.ch/dok/A6070625

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The design, preparation and characterisation of a library of malachite green (MG) derivatives for two-photon RNA labelling is described. Some of these MG derivatives exhibit an increased affinity for an MG-aptamer, as well as improved two-photon sensitivity when compared to the classical malachite green chloride. The underlying mechanisms and potential benefits for in vivo RNA visualisation are discussed.
Faculties and Departments:05 Faculty of Science > Departement Umweltwissenschaften > Ehemalige Einheiten Umweltwissenschaften > Pflanzenphysiologie Pathogenabwehr (Boller)
UniBasel Contributors:Heinlein, Manfred
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:01 Mar 2013 11:13
Deposited On:01 Mar 2013 11:09

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