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SPECT-CT compared with conventional imaging modalities for the assessment of the varus and valgus malaligned hindfoot

Knupp, Markus and Pagenstert, Geert I. and Barg, Alexej and Bolliger, Lilianna and Easley, Mark E. and Hintermann, Beat. (2009) SPECT-CT compared with conventional imaging modalities for the assessment of the varus and valgus malaligned hindfoot. Journal of orthopaedic research, Vol. 27. pp. 1461-1466.

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Official URL: http://edoc.unibas.ch/dok/A6005806

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Abstract

The combined single-photon emission computed tomography and conventional computed tomography (SPECT/CT) technique has increased the sensitivity and specificity of bone scans. We examined the value of using SPECT/CT for the assessment of coronal plane hindfoot deformities. Twenty-seven patients with varus (11 patients) or valgus (16 patients) malalignment of the hindfoot were assessed using radiography, conventional CT, bone scintigraphy, and SPECT/CT. The amount of deformity, stage of osteoarthritis, and level of activation on bone scans and SPECT/CT were measured. Activation was assessed in 12 regions of interest. The stage of osteoarthritis seen on plain radiographs correlated significantly with the level of activation detected on bone scans (p > 0.05). No correlation was observed between the amount of deformation and activity, and between bone scan activation and signs of osteoarthritis on CT scans. The varus malaligned ankles showed higher radioisotope uptake in the medial areas, while the valgus malaligned ankles showed increased uptake in the lateral areas (p > 0.05). SPECT/CT may be a valuable tool for the assessment and staging of osteoarthritis. Our findings underline the adverse effects of coronal plane deformity of the hindfoot. In addition, results from this study provide useful information for future basic research on coronal plane deformity of the hindfoot and for determining appropriate surgical approaches.
Faculties and Departments:03 Faculty of Medicine > Bereich Operative Fächer (Klinik) > Bewegungsapparat und Integument
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Operative Fächer (Klinik) > Bewegungsapparat und Integument
UniBasel Contributors:Hintermann, Beat
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:John Wiley
ISSN:0736-0266
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:01 Mar 2013 11:13
Deposited On:01 Mar 2013 11:08

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