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X-ray studies of biological matter in microfluidic environments

Koester, Sarah and Pfohl, Thomas. (2012) X-ray studies of biological matter in microfluidic environments. Modern physics letters B, 26 (26). p. 1230018.

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Official URL: http://edoc.unibas.ch/dok/A6070569

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Abstract

Biological systems such as cells and cellular components are governed by processes, which take place on nanometer to micrometer length scales. X-ray scattering, diffraction and imaging techniques are extremely well suited to study these processes as the spatial resolution extends well into the relevant length scales. At the same time, the investigation of physical and chemical properties and behavior of such systems requires well-defined and controllable sample environments. One successful way to establish such environments, including specified flow fields, concentration gradients and confinement regimes is by employing microfluidic technology tailored to the particular scientific question. This brief review focuses on microfluidic techniques that have been used to investigate biological matter by X-rays. In particular, we show how the characteristics of flow on the micron scale enable new scientific approaches as compared to macroscale experiments.
Faculties and Departments:05 Faculty of Science > Departement Chemie > Chemie > Biophysikalische Chemie (Pfohl)
UniBasel Contributors:Pfohl, Thomas
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:World Scientific Publishing
ISSN: 0217-9849
e-ISSN:1793-6640
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Identification Number:
Last Modified:16 Feb 2017 10:23
Deposited On:01 Feb 2013 08:44

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