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Stimuli-responsive polymers and their applications in nanomedicine

Cabane, E. and Zhang, X. Y. and Langowska, K. and Palivan, C. G. and Meier, W.. (2012) Stimuli-responsive polymers and their applications in nanomedicine. Biointerphases, 7 (9). p. 28.

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Official URL: http://edoc.unibas.ch/dok/A6070452

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Abstract

This review focuses on smart nano-materials built of stimuli-responsive (SR) polymers and will discuss their numerous applications in the biomedical field. The authors will first provide an overview of different stimuli and their corresponding, responsive polymers. By introducing myriad functionalities, SR polymers present a wide range of possibilities in the design of stimuli-responsive devices, making use of virtually all types of polymer constructs, from self-assembled structures (micelles, vesicles) to surfaces (polymer brushes, films) as described in the second section of the review. In the last section of this review the authors report on some of the most promising applications of stimuli-responsive polymers in nanomedicine. In particular, we will discuss applications pertaining to diagnosis, where SR polymers are used to construct sensors capable of selective recognition and quantification of analytes and physical variables, as well as imaging devices. We will also highlight some examples of responsive systems used for therapeutic applications, including smart drug delivery systems (micelles, vesicles, dendrimers ... ) and surfaces for regenerative medicine.
Faculties and Departments:05 Faculty of Science > Departement Chemie
05 Faculty of Science > Departement Chemie > Chemie > Makromolekulare Chemie (Meier)
UniBasel Contributors:Meier, Wolfgang P.
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:AIP Publishing
ISSN:1934-8630
e-ISSN:1559-4106
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Identification Number:
Last Modified:16 Feb 2017 09:49
Deposited On:01 Feb 2013 08:44

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