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Treatment of hepatitis C in HCV mono-infected and in HIV-HCV co-infected patients : an open-labelled comparison study

Gonvers, Jean-Jacques and Heim, Markus H. and Cavassini, Matthias and Müllhaupt, Beat and Genné, Daniel and Bernasconi, Enos and Borovicka, Jan and Cerny, Andreas and Chave, Jean-Philippe and Chuard, Christian and Dufour, François and Dutoit, Valérie and Malinverni, Raffaelle and Monnat, Martine and Negro, Francesco and Troilliet, Nicolas and Oneta, Carl. (2010) Treatment of hepatitis C in HCV mono-infected and in HIV-HCV co-infected patients : an open-labelled comparison study. Swiss Medical Weekly, Vol. 140 , w13055.

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Official URL: http://edoc.unibas.ch/dok/A6003051

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Abstract

Treatment of chronic HCV infection has become a priority in HIV+ patients, given the faster progression to end-stage liver disease. The primary endpoint of this study was to evaluate and compare antiviral efficacy of Peginterferon alpha 2a plus ribavirin in HIV-HCV co-infected and HCV mono-infected patients, and to examine whether 6 months of therapy would have the same efficacy in HIV patients with favourable genotypes 2 and 3 as in mono-infected patients, to minimise HCV-therapy-related toxicities. Secondary endpoints were to evaluate predictors of sustained virological response (SVR) and frequency of side-effects.
Faculties and Departments:03 Faculty of Medicine > Departement Biomedizin > Department of Biomedicine, University Hospital Basel > Hepatology Laboratory (Heim)
UniBasel Contributors:Heim, Markus H.
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:EMH
ISSN:1424-7860
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:01 Feb 2013 08:46
Deposited On:01 Feb 2013 08:43

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