Prevalence of long and short QT in a young population of 41,767 predominantly male Swiss conscripts

Kobza, Richard and Roos, Markus and Niggli, Bernhard and Abächerli, Roger and Lupi, Gianpiero A. and Frey, Franz and Schmid, Johann Jakob and Erne, Paul. (2009) Prevalence of long and short QT in a young population of 41,767 predominantly male Swiss conscripts. Heart rhythm : the official journal of the Heart Rhythm Society, Vol. 6. pp. 652-657.

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Official URL: http://edoc.unibas.ch/dok/A6005294

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BACKGROUND: Abnormally long and short QT intervals are recognized to be associated with an increased risk for life-threatening ventricular arrhythmias. It is therefore important to define the upper and lower border of the normal QT. OBJECTIVE: The aim of this study was to describe the normal distribution of the QT interval in a contemporary population of young conscripts and to define long and short limits of the QT interval. METHODS: In Switzerland, all young male citizens must undergo compulsory conscription for the Swiss Army at the age of 18 to 19 years. In every conscript, an electrocardiogram (ECG) is performed. Retrospectively, 41,767 consecutive ECGs of Swiss citizens who underwent conscription for the army between March 1, 2004, and July 31, 2006, were analyzed. RESULTS: The mean QTc Bazett interval was 394 +/- 22 ms. One percent of the conscripts had a Bazett QTc shorter than 347 ms, and one percent had a Bazett QTc longer than 445 ms, respectively. None of the subjects presented a QTc Bazett > 300 ms; the prevalence of a QTc Bazett > 320 ms was 0.02%. CONCLUSION: The present study shows the distribution of QT intervals in an unselected young population. Because none of the subjects presented a QTc > 300 ms, it may be concluded that the short QT syndrome is a very rare entity in the population of young male adults.
Faculties and Departments:03 Faculty of Medicine > Departement Biomedizin > Further Research Groups at DBM > Signal Transduction (Resink/Erne)
UniBasel Contributors:Erne, Paul
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:01 Feb 2013 08:46
Deposited On:01 Feb 2013 08:42

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