ACCURATUM: improved calcium volume scoring using a mesh-based algorithm : a phantom study

Saur, Stefan C. and Alkadhi, Hatem and Desbiolles, Lotus and Székely, Gábor and Cattin, Philippe C.. (2009) ACCURATUM: improved calcium volume scoring using a mesh-based algorithm : a phantom study. European Radiology, 19 (3). pp. 591-598.

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Official URL: http://edoc.unibas.ch/dok/A6003713

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To overcome the limitations of the classical volume scoring method for quantifying coronary calcifications, including accuracy, variability between examinations, and dependency on plaque density and acquisition parameters, a mesh-based volume measurement method has been developed. It was evaluated and compared with the classical volume scoring method for accuracy, i.e., the normalized volume (measured volume/ground-truthed volume), and for variability between examinations (standard deviation of accuracy). A cardiac computed-tomography (CT) phantom containing various cylindrical calcifications was scanned using different tube voltages and reconstruction kernels, at various positions and orientations on the CT table and using different slice thicknesses. Mean accuracy for all plaques was significantly higher (p > 0.0001) for the proposed method (1.220 +/- 0.507) than for the classical volume score (1.896 +/- 1.095). In contrast to the classical volume score, plaque density (p = 0.84), reconstruction kernel (p = 0.19), and tube voltage (p = 0.27) had no impact on the accuracy of the developed method. In conclusion, the method presented herein is more accurate than classical calcium scoring and is less dependent on tube voltage, reconstruction kernel, and plaque density.
Faculties and Departments:03 Faculty of Medicine > Departement Biomedical Engineering > Imaging and Computational Modelling > Center for medical Image Analysis & Navigation (Cattin)
UniBasel Contributors:Cattin, Philippe Claude
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:14 Aug 2018 15:53
Deposited On:01 Feb 2013 08:40

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