The European baseline series in 10 European Countries, 2005/2006 : results of the European Surveillance System on Contact Allergies (ESSCA)

Uter, Wolfgang and Rämsch, Christiane and Aberer, Werner and Ayala, Fabio and Balato, Anna and Beliauskiene, Aiste and Fortina, Anna Belloni and Bircher, Andreas and Brasch, Jochen and Chowdhury, Mahbub M. U. and Coenraads, Pieter-Jan and Schuttelaar, Marie-Louise and Cooper, Sue and Corradin, Maria Teresa and Elsner, Peter and English, John S. C. and Fartasch, Manigè and Mahler, Vera and Frosch, Peter J. and Fuchs, Thomas and Gawkrodger, David J. and Gimènez-Arnau, Ana-Maria and Green, Cathy M. and Horne, Helen L. and Jolanki, Riitta and King, Codagh M. and Krêcisz, Beata and Kiec-Swierczynska, Marta and Ormerod, Anthony D. and Orton, David I. and Peserico, Andrea and Rantanen, Tapio and Rustemeyer, Thomas and Sansom, Jane E. and Simon, Dagmar and Statham, Barry N. and Wilkinson, Mark and Schnuch, Axel. (2009) The European baseline series in 10 European Countries, 2005/2006 : results of the European Surveillance System on Contact Allergies (ESSCA). Contact dermatitis, Vol. 61. pp. 31-38.

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Official URL: http://edoc.unibas.ch/dok/A6004153

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BACKGROUND: Continual surveillance based on patch test results has proved useful for the identification of contact allergy. OBJECTIVES: To provide a current view on the spectrum of contact allergy to important sensitizers across Europe. PATIENTS/METHODS: Clinical and patch test data of 19 793 patients patch tested in 2005/2006 in the 31 participating departments from 10 European countries (the European Surveillance System on Contact Allergies' (ESSCA) www.essca-dc.org) were descriptively analysed, aggregated to four European regions. RESULTS: Nickel sulfate remains the most common allergen with standardized prevalences ranging from 19.7% (central Europe) to 24.4% (southern Europe). While a number of allergens shows limited variation across the four regions, such as Myroxylon pereirae (5.3-6.8%), cobalt chloride (6.2-8.8%) or thiuram mix (1.7-2.4%), the differences observed with other allergens may hint on underlying differences in exposures, for example: dichromate 2.4% in the UK (west) versus 4.5-5.9% in the remaining EU regions, methylchloroisothiazolinone/methylisothiazolinone 4.1% in the South versus 2.1-2.7% in the remaining regions. CONCLUSIONS: Notwithstanding residual methodological variation (affecting at least some 'difficult' allergens) tackled by ongoing efforts for standardization, a comparative analysis as presented provides (i) a broad overview on contact allergy frequencies and (ii) interesting starting points for further, in-depth investigation.
Faculties and Departments:03 Faculty of Medicine > Bereich Spezialfächer (Klinik) > Dermatologie USB > Dermatologie (Bircher)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Spezialfächer (Klinik) > Dermatologie USB > Dermatologie (Bircher)
UniBasel Contributors:Bircher, Andreas J.
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:04 Jan 2013 08:38
Deposited On:04 Jan 2013 08:37

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