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Tubular toxicity in sirolimus- and cyclosporine-based transplant immunosuppression strategies : an ancillary study from a randomized controlled trial

Franz, Stefan and Regeniter, Axel and Hopfer, Helmut and Mihatsch, Michael and Dickenmann, Michael. (2010) Tubular toxicity in sirolimus- and cyclosporine-based transplant immunosuppression strategies : an ancillary study from a randomized controlled trial. American journal of kidney diseases, Vol. 55, H. 2. pp. 335-343.

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Official URL: http://edoc.unibas.ch/dok/A6003760

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Abstract

Sirolimus has been promoted as an agent to provide immunosuppression for kidney transplant recipients that, in contrast to calcineurin inhibitors, would not be nephrotoxic. However, several reports have observed proteinuria in patients treated with sirolimus, ranging from low grade to nephrotic range. Accordingly, we compared markers of tubular and glomerular damage in an ancillary study of a randomized trial comparing sirolimus and cyclosporine.
Faculties and Departments:03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Nephrologie > Transplantationsimmunologie und Nephrologie (Steiger)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Nephrologie > Transplantationsimmunologie und Nephrologie (Steiger)
UniBasel Contributors:Dickenmann, Michael Jan
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
ISSN:0272-6386
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:07 Dec 2012 13:03
Deposited On:07 Dec 2012 13:01

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