The impact of statin treatment on presentation mode and early outcomes in acute coronary syndromes

Cuculi, F. and Radovanovic, D. and Eberli, F. R. and Stauffer, J. C. and Bertel, O. and Erne, P. and Amis, Plus Investigators. (2008) The impact of statin treatment on presentation mode and early outcomes in acute coronary syndromes. Cardiology, 109 (3). pp. 156-162.

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Official URL: http://edoc.unibas.ch/dok/A6006124

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OBJECTIVES: The role of statin use in the treatment of acute coronary syndromes (ACS) is not clear. The aim of our study was to evaluate the role of statins in ACS. METHODS: Using data from the Acute Myocardial Infarction in Switzerland (AMIS Plus) Project, we compared the effects of chronic statin use, statin therapy after admission and no statin therapy on presentation mode and outcomes in ACS. RESULTS: Available data from the period 2001-2006 including 11,603 patients were analyzed. Major cardiac event rates and in-hospital mortality were more common in statin-naive patients compared to patients who received statins. CONCLUSIONS: Our results support the importance of statin treatment in ACS. Chronic statin therapy seems to alter the initial presentation of ACS but it is questionable whether it provides an additional effect on early outcomes compared to the establishment of statin therapy after admission in statin-naive patients.
Faculties and Departments:03 Faculty of Medicine > Departement Biomedizin > Further Research Groups at DBM > Signal Transduction (Resink/Erne)
UniBasel Contributors:Erne, Paul
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:S. Karger
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:25 Oct 2017 08:37
Deposited On:07 Dec 2012 13:00

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