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Rapid and reliable diagnostic algorithm for detection of Clostridium difficile

Fenner, L. and Widmer, A. F. and Goy, G. and Rudin, S. and Frei, R.. (2008) Rapid and reliable diagnostic algorithm for detection of Clostridium difficile. Journal of clinical microbiology, Vol. 46, H. 1. pp. 328-330.

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Official URL: http://edoc.unibas.ch/dok/A6004231

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Abstract

We evaluated a two-step algorithm for detection of Clostridium difficile in 1,468 stool specimens. First, specimens were screened by an immunoassay for C. difficile glutamate dehydrogenase antigen (C.DIFF CHEK-60). Second, screen-positive specimens underwent toxin testing by a rapid toxin A/B assay (TOX A/B QUIK CHEK); toxin-negative specimens were subjected to stool culture. This algorithm allowed final results for 92% of specimens with a turnaround time of 4 h.
Faculties and Departments:03 Faculty of Medicine > Bereich Querschnittsfächer (Klinik) > Labormedizin > Klinische Mikrobiologie (Frei)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Querschnittsfächer (Klinik) > Labormedizin > Klinische Mikrobiologie (Frei)
03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Infektiologie > Infektiologie (Battegay M)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Infektiologie > Infektiologie (Battegay M)
UniBasel Contributors:Widmer, Andreas F.-X. and Frei, Reno
Item Type:Article, refereed
Article Subtype:Research Article
ISSN:1098-660X
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:08 Nov 2012 16:23
Deposited On:08 Nov 2012 16:18

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