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Polymer-protein core-shell hybrids for controlled siRNA delivery

Nussbaumer, Martin G. and Bruns, Nico. (2011) Polymer-protein core-shell hybrids for controlled siRNA delivery. Polymer Preprints / American Chemical Society, Division of Polymer Chemistry, Vol. 52. pp. 187-188.

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Official URL: http://edoc.unibas.ch/dok/A6002607

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Abstract

Polymer PAMAM-protein core shell composite was developed as a pharmaceutical carrier for siRNA. Conjugation of PAMAM with thermosome chaperonin of Thermoplasma acidophilum was achieved by using PAMAM HyNic and thermosome functionalized with MTFB. SiRNA was encapsulated into the the formed PAMAM thermosome core shell hybrid.
Faculties and Departments:05 Faculty of Science > Departement Chemie > Chemie
05 Faculty of Science > Departement Chemie > Chemie > Makromolekulare Chemie (Meier)
UniBasel Contributors:Bruns, Nico
Item Type:Article
Article Subtype:Research Article
Bibsysno:Link to catalogue
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:04 Sep 2015 14:31
Deposited On:11 Oct 2012 15:25

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