edoc

Dorsolateral and ventromedial prefrontal cortex orchestrate normative choice

Baumgartner, T. and Knoch, D. and Hotz, P. and Eisenegger, C. and Fehr, E.. (2011) Dorsolateral and ventromedial prefrontal cortex orchestrate normative choice. Nature neuroscience, Vol. 14. pp. 1468-1474.

Full text not available from this repository.

Official URL: http://edoc.unibas.ch/dok/A5844722

Downloads: Statistics Overview

Abstract

Humans are noted for their capacity to over-ride self-interest in favor of normatively valued goals. We examined the neural circuitry that is causally involved in normative, fairness-related decisions by generating a temporarily diminished capacity for costly normative behavior, a 'deviant' case, through non-invasive brain stimulation (repetitive transcranial magnetic stimulation) and compared normal subjects' functional magnetic resonance imaging signals with those of the deviant subjects. When fairness and economic self-interest were in conflict, normal subjects (who make costly normative decisions at a much higher frequency) displayed significantly higher activity in, and connectivity between, the right dorsolateral prefrontal cortex (DLPFC) and the posterior ventromedial prefrontal cortex (pVMPFC). In contrast, when there was no conflict between fairness and economic self-interest, both types of subjects displayed identical neural patterns and behaved identically. These findings suggest that a parsimonious prefrontal network, the activation of right DLPFC and pVMPFC, and the connectivity between them, facilitates subjects' willingness to incur the cost of normative decisions.
Faculties and Departments:07 Faculty of Psychology > Departement Psychologie > Ehemalige Einheiten Psychologie > Social and Affective Neuroscience (Knoch)
UniBasel Contributors:Knoch, Daria and Baumgartner, Thomas
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Nature America
ISSN:1097-6256
Note:Publication type according to Uni Basel Research Database: Journal article
Related URLs:
Identification Number:
Last Modified:01 Mar 2013 11:07
Deposited On:14 Sep 2012 07:04

Repository Staff Only: item control page