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"The heat is on" : rapid microcalorimetric detection of mycobacteria in culture

Braissant, O. and Wirz, D. and Göpfert, B. and Daniels, A. U.. (2010) "The heat is on" : rapid microcalorimetric detection of mycobacteria in culture. Tuberculosis, Vol. 90, H. 1. pp. 57-59.

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Official URL: http://edoc.unibas.ch/dok/A5841580

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Abstract

Detection of mycobacterial infection can be achieved by different means; however, culture-based methods remain the gold standard. In this paper, we present a new culture-based method using real-time microcalorimetric detection of growth of Mycobacterium species including Mycobacterium tuberculosis. Microcalorimetric detection of heat production by 6 different growing species of Mycobacterium was achieved between 20 and 310h depending on their type (fast vs. slow-growing mycobacteria) and initial concentration. This study demonstrates that microcalorimetric detection of mycobacterial growth is a potential advantageous alternative to methods using fluorescent or radiolabeled growth indicators.
Faculties and Departments:03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Rheumatologie
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Rheumatologie
03 Faculty of Medicine
UniBasel Contributors:Daniels, A.U. Dan and Göpfert, Beat and Wirz, Dieter
Item Type:Article
Article Subtype:Book Review
Bibsysno:Link to catalogue
Publisher:Elsevier
ISSN:1472-9792
Note:Publication type according to Uni Basel Research Database: Journal item
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Last Modified:16 Aug 2013 07:34
Deposited On:14 Sep 2012 07:01

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