# 3,3 -Bis(arylbenzofurans) via a Gold-Catalyzed Domino Process

Auzias, Mathieu G. and Neuburger, Markus and Wegner, Hermann A.. (2010) 3,3 -Bis(arylbenzofurans) via a Gold-Catalyzed Domino Process. Synlett, 2010, Vol. 16. pp. 2443-2448.

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Official URL: http://edoc.unibas.ch/dok/A5841483

A new heterogeneous gold-catalyzed system for the domino cyclization oxidative coupling of 2-alkynyl phenols for the formation of 3,3-bisbenzofurans was developed. The substrate and the catalyst scope as well as the reaction conditions were investigated and optimized. This method provides access to this novel structural theme in two steps starting from commercially available chemicals. The molecular structure of the 3,3-bisbenzofurans was confirmed by single-crystal X-ray analysis.