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Kongenitale Langerhans-Zellen-Histiozytose unter dem klinischen Bild einer Varizelleninfektion

Girisch, M. and Fartasch, M. and Schroth, M. and Rauch, R. and Leipold, G. and Franz, K. and Heininger, U.. (1999) Kongenitale Langerhans-Zellen-Histiozytose unter dem klinischen Bild einer Varizelleninfektion. Klinische Pädiatrie, Vol. 211, H. 5. pp. 403-405.

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Official URL: http://edoc.unibas.ch/dok/A5839191

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Abstract

We report on a preterm infant (33rd gestational week) with a varicella-like congenital rash, which initially appeared to respond to therapy with acyclovir. At the age of 3 weeks, lesions were in different stages of evolution and still resembled a varicella zoster virus (VZV) infection. However, since proof of VZV infection was lacking and new lesions erupted at the age of 4 weeks, a skin biopsy was performed which revealed a diagnosis of Langerhans cells histiocytosis. Therapy with prednisone resulted in prompt healing of the lesions. DISCUSSION: Congenital Langerhans cell histiocytosis is rare and symptoms may vary substantially from case to case. Like in our observation it may be confused with congenital varicella. In case of congenital skin lesions of uncertain etiology a skin biopsy should be performed
Faculties and Departments:03 Faculty of Medicine > Bereich Kinder- und Jugendheilkunde (Klinik) > Kinder- und Jugendheilkunde (UKBB)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Kinder- und Jugendheilkunde (Klinik) > Kinder- und Jugendheilkunde (UKBB)
UniBasel Contributors:Heininger, Ulrich
Item Type:Article, refereed
Article Subtype:Book Review
Bibsysno:Link to catalogue
Publisher:Enke
ISSN:0300-8630
Note:Note: Englischer Titel: Congenital Langerhans-cell histiocytosis presenting as a varicella infection -- Publication type according to Uni Basel Research Database: Journal item
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Last Modified:14 Sep 2012 07:19
Deposited On:14 Sep 2012 06:57

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