Shepherd, J. C. and Walldorf, U. and Hug, P. and Gehring, W. J.. (1989) Fruit flies with additional expression of the elongation factor EF-1 alpha live longer. Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, H. 19. pp. 7520-7521.
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Official URL: http://edoc.unibas.ch/dok/A5257334
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Abstract
In Drosophila melanogaster, the decrease in protein synthesis that accompanies aging is preceded by a decrease in elongation factor EF-1 alpha protein and mRNA. Here we show that Drosophila transformed with a P-element vector containing an EF-1 alpha gene under control of hsp70 regulatory sequences have a longer life-span than control flies.
| Faculties and Departments: | 05 Faculty of Science > Departement Biozentrum > Former Organization Units Biozentrum > Cell Biology (Gehring) |
|---|---|
| UniBasel Contributors: | Gehring, Walter Jakob |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | National Academy of Sciences |
| ISSN: | 0027-8424 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
| Last Modified: | 22 Mar 2012 14:19 |
| Deposited On: | 22 Mar 2012 13:17 |
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