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A functional genetic variation of the 5-HT2a receptor affects human memory

de Quervain, Dominique J.-F. and Henke, Katharina and Aerni, Amanda and Coluccia, Daniel and Wollmer, M. Axel and Hock, Christoph and Nitsch, Roger M. and Papassotiropoulos, Andreas. (2003) A functional genetic variation of the 5-HT2a receptor affects human memory. Nature Neuroscience, Vol. 6, H. 11. pp. 1141-1142.

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Official URL: http://edoc.unibas.ch/dok/A5257179

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Abstract

Human memory capacity is highly variable across individuals and is influenced by both genetic and environmental factors. A roughly 50% heritability estimate indicates that naturally occurring genetic variations have an important impact on this cognitive ability. Therefore, we investigated a functional variation of a memory-related serotonin receptor in 349 healthy young volunteers, and found 21% poorer memory performance in subjects with the rare variant.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Services Biozentrum > Life Sciences Training Facility (Papassotiropoulos)
07 Faculty of Psychology > Departement Psychologie > Forschungsbereich Klinische Psychologie und Neurowissenschaften > Molecular Psychology (Papassotiropoulos)
UniBasel Contributors:Papassotiropoulos, Andreas and de Quervain, Dominique J.-F.
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Nature America
ISSN:1097-6256
e-ISSN:1546-1726
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:23 Nov 2017 10:02
Deposited On:22 Mar 2012 13:17

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