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Oligonucleotide nanostructured surfaces : effect on escherichia coli curli expression

Cottenye, Nicolas and Teixeira, Jr. and Francisco, and Ponche, Arnaud and Reiter, Guenter and Anselme, Karine and Meier, Wolfgang and Ploux, Lydie and Vebert-Nardin, Corinne. (2008) Oligonucleotide nanostructured surfaces : effect on escherichia coli curli expression. Macromolecular bioscience, Vol. 8, H. 12. pp. 1161-1172.

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Official URL: http://edoc.unibas.ch/dok/A5251057

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Abstract

Oligonucleotide model surfaces allowing independent variation of topography and chemical composition were designed to study the adhesion and biofilm growth of E.coli. Surfaces were produced by covalent binding of oligonucleotides and immobilization of nucleotide-based vesicles. Their properties were confirmed through a combination of fluorescence microscopy, XPS, ellipsometry, AFM and wettability Studies at each step of the process. These sur-faces were then used to study the response of three different strains of E.coli quantified in a static biofilm growth mode. This study led to convincing evidence that oligonucleotide-modified surfaces, independent of the topographical feature used in this study, enhanced curli expression without an increase in the number of adherent bacteria.
Faculties and Departments:05 Faculty of Science > Departement Chemie > Chemie > Makromolekulare Chemie (Meier)
UniBasel Contributors:Meier, Wolfgang P.
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Wiley-VCH
ISSN:1616-5195
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:14 Sep 2012 06:56
Deposited On:22 Mar 2012 14:07

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